A RIBODEPLETION AND TAGGING PROTOCOL TO MULTIPLEX SAMPLES FOR RNA-SEQ BASED VIRUS DETECTION: APPLICATION TO THE CASSAVA VIROME

A ribodepletion and tagging protocol to multiplex samples for RNA-seq based virus detection: application to the cassava virome

Abstract Background Cassava (Manihot esculenta, Crantz), is a staple food and the main source of calories for many populations in Africa, but the plant is beset by several damaging viruses.So far, eight families of virus infecting cassava have been identified; the Geminiviridae (ssDNA viruses responsible for cassava mosaic disease, CMD) and Potyvir

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Anti-Idiotypic mRNA Vaccine to Treat Autoimmune Disorders

The 80+ existing autoimmune disorders (ADs) affect billions with little prevention or treatment options, except for temporary symptomatic management, leading to enormous human suffering and a monumental financial burden.The autoantibodies formed in most ADs have been identified, allowing the development of novel anti-idiotypic antibodies to PINK GR

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